Pacira BioSciences is a biopharmaceutical company that develops and commercializes non-opioid pain management therapies across three main product categories: EXPAREL, a long-acting local anesthetic for postsurgical pain relief; ZILRETTA, an extended-release intra-articular corticosteroid for osteoarthritis knee pain; and iovera°, a handheld cryoneurolysis device for drug-free nerve-targeted pain management. The company generates revenue primarily through direct product sales to healthcare wholesalers and end-users, as well as royalties from licensed partnerships, and serves patients across orthopedic, abdominal, colorectal, and other surgical settings while advancing a pipeline of gene therapy candidates for osteoarthritis. Pacira's competitive position rests on extensive patent protection for its proprietary formulation and device technologies, combined with clinical data demonstrating significant opioid-sparing benefits across its portfolio.