Pacific Biosciences is a life science technology company that designs, develops, and manufactures advanced genomic sequencing systems based on proprietary Single-Molecule Real-Time (SMRT) technology. The company offers HiFi long-read sequencing instruments (Revio, Vega, and Sequel systems), proprietary SMRT Cell microfluidic consumables, reagent kits, and sequencing services that enable accurate detection of genetic variation, epigenetic status, and structural variants across diverse applications in human genomics, infectious disease, oncology, and agricultural research. PacBio generates revenue through instrument sales and recurring consumables revenue, leveraging an installed base of customers spanning academic institutions, commercial laboratories, genomic centers, hospitals, pharmaceutical companies, and agricultural enterprises that purchase proprietary SMRT Cells and reagent kits for each sequencing experiment.