Nautilus Biotechnology is a life sciences company developing a proteomics platform technology called Nautilus Voyager that uses single-molecule measurement to detect and quantify the complete set of proteins in biological samples—a capability that has historically lagged behind genomics and transcriptomics tools. The integrated platform combines specialized instrumentation, consumable flow cells and reagents, and cloud-based machine learning software to enable both broadscale proteome analysis and targeted characterization of protein variants and modifications, serving academic research institutions, pharmaceutical companies, and multi-omics centers. The company generates revenue through multiple streams including instrument sales, recurring consumables, cloud-based software subscriptions, and professional services, employing a controlled market entry strategy that encourages customers to expand from targeted applications to comprehensive proteomics analysis.